By Mike Wells; Lara Goldstein; Martin J Botha
The best way to use this e-book -- Overcoming drugs blunders in paediatric emergencies -- management, teamwork, and resuscitation aids -- sensible pharmacology in paediatric emergencies -- Emergency bolus drug dosing charts -- Emergency infusions dosing charts -- Drug dosing directions : pearls and pitfalls -- gear directions : pearls and pitfalls -- necessary formulation and knowledge for handling paediatric emergencies
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Additional resources for Emergency drug dosing in children : a resuscitation aid for paediatric emergencies
Higher stat doses will have little negative consequence beyond prolonging the duration of action. Titrate to effect (*will affect haemodynamics more). Use TBW for the dose recommended in this book which is at the lower edge of the range. Tips and tricks 4 Practical pharmacology in paediatric emergencies Dose modification for developmental stage 4 Developmental stage Drug doses for neonates and infants may need to be relatively higher in mg/kg values than for older children – be prepared to repeat a dose or to administer slightly higher doses than expected.
5mg/1mL + 9mL dil. 05mg/mL) Obidoxime 4mg/kg 20 250mg/1mL + 19mL dil. 15mg/kg 10 4mg/2mL + 8mL dil. 1mg/kg 10 4mg/2mL + 8mL dil. 4mg/mL) Pantoprazole 2mg/kg 10 40mg/2mL + 8mL dil. (4mg/mL) Paracetamol 15mg/kg 10 10mg/mL undiluted Phenobarbitone 10mg/kg 10 200mg/1mL + 9mL dil. (20mg/mL) 50 250mg/5mL + 45mL dil. (5mg/mL) Platelets 10mL/kg Adjust dose to indication; warm before use Potassium IV/IO for severe hypokalaemia Pralidoxime 25mg/kg 5 KCl 15% (2mmol/mL) - give SLOWLY 20 1g in 20mL dil. 5mg/kg 1 10 25mg/1mL + 9mL dil.
About 75% of drugs used in paediatrics have never been studied in children. PHARMACOKINETICS IN CRITICAL ILLNESS Some general pharmacokinetic principles that are relevant to emergency drug administration in critically ill children: Hypoxaemia as well as poor perfusion leads to decreased or unpredictable drug absorption from the GIT. This, in addition to variable first pass metabolism, is one of the reasons that intravenous administration is favoured to ensure optimum bioavailability of the drug.
Emergency drug dosing in children : a resuscitation aid for paediatric emergencies by Mike Wells; Lara Goldstein; Martin J Botha