Get DNA: Promise and Peril PDF

By Linda L. McCabe, Edward R. B. McCabe

ISBN-10: 0520251873

ISBN-13: 9780520251878

Victor McKusick (Foreword)

The genetic revolution has supplied quite necessary information regarding our DNA, info that may be used to learn and inform—but additionally to pass judgement on, discriminate, and abuse. a vital reference for residing in today's global, this booklet supplies the heritage details severe to realizing how genetics is now affecting our daily lives. Written in transparent, vigorous language, it offers a finished view of interesting fresh discoveries and explores the moral, criminal, and social matters that experience arisen with every one new development.


“Goes a ways towards exploring those concerns in a painstaking but readable scholarly treatise. . . . all through, they make a resounding case that we're not our genome alone.”
(New England magazine of medication 2008-10-23)

“The publication is something yet dry reporting. . . . An relaxing and stimulating learn for experts within the box and the curious public alike.”
(Science (AAAS) 2009-08-14)

“Readers will come away with a practical and inspiring viewpoint on scientific genetics, delivering that neither significant optimism nor abject worry is important to make the genuine tale of DNA exciting.”
(Qtly overview Of Biology 2011-03-01)

“Readers will come away with a pragmatic and inspiring standpoint on clinical genetics, proving that neither incredible optimism nor abject worry is important to make the genuine tale of DNA exciting.”
(Qtly evaluate Of Biology 2011-05-04)

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Additional resources for DNA: Promise and Peril

Example text

In 1944, Oswald Avery, Colin MacLeod, and Maclyn McCarty showed that DNA was the hereditary material by demonstrating that it mediated the transformation of cellular properties when it was introduced into cells. In 1953, working in the Cavendish Laboratory at Cambridge University, James Watson and Francis Crick reported the double helical structure of DNA. Their description, though very brief, was a tour de force in structural biology that included X-ray diffraction of crystallized DNA. ” In 1962, Crick, Watson, and Maurice Wilkins shared the Nobel Prize in Physiology or Medicine for their work to solve the structure of DNA.

It is diYcult to change human behavior. Examples are seen in the challenges faced in preventing and managing obesity and smoking. In addition, some individuals may not want to know their genetic futures. ” A change in the paradigm of medicine will require major changes in the thinking of the public and physicians. It is also possible to misuse sequence information. Every study of public opinion about genetics indicates signiWcant fear of genetic discrimination by use of genetic information to limit employment or insurance (chapter 10).

Watson also made the following statement at a conference held at the University of California, Los Angeles (UCLA), “Engineering the Human Germline,” which was quoted in a book edited by Greg Stock and John Campbell and published in 2000: “And the other thing, because no one has the guts to say it, if we could make better human beings by knowing how to add genes, why shouldn’t we? What’s wrong with it? . Evolution can be just damn cruel, and to say that we’ve got a perfect genome and there’s some sanctity to it?

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DNA: Promise and Peril by Linda L. McCabe, Edward R. B. McCabe

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