By Elliott M. Antman MD
Manage cardiovascular difficulties extra effectively with the main complete source to be had! A relied on spouse to Braunwald's middle Disease, Cardiovascular Therapeutics, 4th Edition addresses pharmacological, interventional, and surgical administration techniques for every form of heart problems. This sensible and clinically centred cardiology reference deals a balanced, whole method of the entire ordinary and strange components of heart problems and particular cures in a single concise quantity, equipping you to make the simplest offerings for each patient.
- Understand present techniques to treating and dealing with cardiovascular patients
- Benefit from the enormous adventure of Elliott M. Antman, MD, Marc S. Sabatine, MD, and a bunch of different revered specialists, who supply useful, evidence-based rationales for all of ultra-modern scientific therapies.
- Expand your wisdom past pharmacologic interventions with entire insurance of the simplest interventional and equipment cures getting used today.
- Easily reference Braunwald's center affliction, ninth Edition for extra details on themes of interest.
for long term well-being, for complicated difficulties, and for strange cardiac events.
- Make the simplest use of the newest genetic and molecular therapies
- Cut correct to the solutions you would like with an better specialize in clinically suitable details and a lowered emphasis on pathophysiology.
- Stay present with ACC/AHA/ESC guidelines and the easiest how you can enforce them in scientific practice.
- Get an better visible perspective with an all-new, full-color layout throughout.
- Access the entire contents online and download images at www.expertconsult.com.
in addition to advanced remedies for middle failure.
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Extra resources for Cardiovascular therapeutics : a companion to Braunwald's Heart disease
Part 1: Ethical and scientiﬁc issues. Ann Intern Med 2000;133:455-63. 46. Ellenberg SS, Temple R: Placebo-controlled trials and activecontrol trials in the evaluation of new treatments. Part 2: Practical issues and speciﬁc cases. Ann Intern Med 2000;133:464-70. 47. Ware JH, Antman EM: Equivalence trials. N Engl J Med 1997;337:1159-61. 48. Greene WL, Concato J, Feinstein AR: Claims of equivalence in medical research: Are they supported by the evidence? Ann Intern Med 2000;132:715-22. 49. Assessment of the Safety and Efﬁcacy of a New Thrombolytic Investigators.
The goal is to enroll a diverse study population in a comparison of clinically relevant alternatives that measure a broad range of health outcomes. 118 Here a sensitivity analysis is used to contrast results from data derived from an RCT (efﬁcacy) with those estimated from community-based observational data (effectiveness) in a CEA of primary angioplasty in acute MI. 118 Although in Figure 1–16 the differences in results between RCT and community-based data depend on volume , in other instances, it may be apparent in all situations.
121 Figure 1–17 illustrates the effect of changing the duration of beneﬁt on the results of CEA. Here an analysis was performed on 6 RCTs of prophylactic implantation of the implantable cardioverter-deﬁbrillator (ICD) in which the device was found to prolong life. The horizontal axis is time of beneﬁt and the vertical axis is cost/QALY. In Figure 1–17A, it was assumed that the ICD conferred no additional beneﬁt after the speciﬁed time on the horizontal axis; lifetime costs were included and survival curves were assumed to be parallel after the time period.
Cardiovascular therapeutics : a companion to Braunwald's Heart disease by Elliott M. Antman MD